Endocrine Abstracts

Introduction: Atrial natriuretic peptide (ANP), a member of the natriuretic peptide family, regulates several physiologic parameters including diuresis and natriuresis, and lowers arterial, blood pressure.It has been reported that plasma concentrations of ANP rise in response to acute hyperglycaemia in diabetes (1) (2) and this may indicate a neurohormonal response to limit target organ damage (3).We investigate if in situation chr...

Introduction: Its has been suggested that atrial natriuretic peptide (ANP) may contribuye to the development of microalbuminuria in diabetes mellitus.Plasma ANP concentration have been reported to be elevated in association with microalbuminuria, all of wich predict the future development of overt nephropathy in diabetes (1).Key players in neurohormonal activation include neuropeptides and their receptors wich include the ANP (2).<...